UBI or ultraviolet blood irradiation is a light treatment which is also known as Photoluminescence, Extracorporeal Photophoresis, Photo-oxidation or UVB Therapy.

Ultraviolet Blood Irradiation (UBI) therapy is a treatment which involves withdrawing a small amount of blood into a syringe and then briefly exposing that blood to selected frequencies of Ultraviolet Light and then re-infusing the blood back into the body. The blood is also treated with a very small amount of medicine to prevent it from clotting (heparin). This treatment is often performed as an add-on therapy to blood that has been mixed with ozone as part of a major autologous hemotherapy (MAH) ozone treatment. However, it can also be done as a single treatment without ozone.

UBI therapy is used clinically as both a specific (ie psoriasis,) and non-specific (chronic infections, chronic fatigue, auto-immune diseases, scleroderma, etc.) treatment. Certain forms of cancer, auto-immune diseases, infections and tissue transplant rejection have all been published as benefiting from Biophotoinc – UBI therapy. Although there are many positive medical studies and testimonies regarding this therapy, this therapy is still largely unknown in the United States and most US physicians would still consider this therapy to be “investigational” or “alternative”.


UBI works via several mechanisms.

1) Exposing blood to ultraviolet light creates an immune stimulating and germicidal effect when it is returned to the body. This generates a chain reaction that regulates the immune system making it more efficient to fight bacterial and viral infections in the body.

2) It may benefit autoimmune conditions by modulating an overactive immune system.


Some research studies have shown the following benefits of UBI Therapy:

  • Increases oxygen absorption into body tissues
  • Destruction of fungal, viral and bacterial growth
  • Enhances the immune system’s ability to fight infection
  • Improves circulation and decreases platelet aggregation
  • Improves circulation by dilating blood vessels
  • Improves the body’s ability to detoxify and inactivate or remove toxins
  • Increase in: arterial and venous oxygenation, blood pH, lymphocytes, electrical charge on the red blood cell, hemoglobin, white blood cell count, lymphocytes, phagocytosis ability
  • Reduction of cholesterol, creatinine levels, blood lactate, clot formation tendencies, blood viscosity, uric acid levels, fibrin levels, plasma viscosity, surface tension of the blood
  • Normalization or modulation of: immune status, glucose tolerance, and fibrinolysis.

Rare but possible complications are the same as those from any injection such as bleeding and infection.
Other possible complications include minor bruising at the injection site, potential minor bleeding from the heparin, mild temporary Herxeimer or “healing reactions” (low grade fever, minor muscle aches or joint aches), and possible prescription drug – UBI interaction, most commonly occurring with sulfa drugs, tetracyclines, and phenothiazines. There is a rare possibility of an allergic reaction which can occur in patients who have an allergy to sunlight.